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Abstract Frailty is an important construct in aging which allows for the identification of the most vulnerable subset of older adults. At least two conceptual models of frailty have been […]
Abstract In developing and validating the concept of frailty as a geriatric syndrome, it has been necessary to distinguish the clinical expression of frailty from normal age-related changes and other […]
Abstract There are inevitable physiologic changes associated with advancing age, yet for some people these changes are exaggerated, and as a result a phenotype emerges recognized as “frailty.” Why some […]
Citation: Walston, Jeremy D. Biological markers and the molecular biology of frailty. Longevity and frailty. Springer, Berlin, Heidelberg, 2005. 83-90. https://www.springer.com/gp/book/9783540251538
Trajectories of health and functioning with age show extreme variability among different individuals. Normal aging implies a progressive decline of physiological reserve and ability to compensate, but it is compatible […]